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Study details
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A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

Janssen Research & Development, LLC
NCT IDNCT07258511ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Ages

18+

Locations

15 sites in CA, CT, FL +7

What this study is about

This Phase 3 study is testing Teclistamab in people with multiple myeloma. The primary outcome being measured is Overall Response Rate (ORR).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

teclistamab

Endpoints

Primary: Overall Response Rate (ORR), Progression-Free Survival (PFS)

Secondary: Change from Baseline in Symptoms, Functioning, and HRQoL as Assessed by European Organization for Research and Treatment of Cancer Quality of life Questionnaire Core 30 (EORTC-QLQ-C30) Score, Change from Baseline in Symptoms, Functioning, and HRQoL as Assessed by European Quality of Life 5-Dimensions 5-Level Version (EQ-5D-5L) Score, Change from Baseline in Symptoms, Functioning, and Health-related Quality of Life (HRQoL) as Assessed by Multiple Myeloma Symptom and Impact Questionnaire (MySIm-Q) Score, Complete Response (CR) or Better, Duration of Response (DoR), MRD-negative CR at 9 months, Minimal Residual Disease (MRD)-negative CR, Number of Participants With Treatment-Emergent Adverse Events (TEAE) by Severity

Body systems

Oncology