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Study details
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Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia

UNC Lineberger Comprehensive Cancer Center
NCT IDNCT07278557ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

98

Study length

about 4.2 years

Ages

18+

Locations

1 site in NC

What this study is about

This trial is testing whether using MRI sialography to spare parotid ducts during radiation therapy reduces dry mouth symptoms in patients with head and neck cancer. It compares this approach to the standard method of sparing the entire parotid gland, focusing on how much dry mouth patients report after treatment.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Undergo Parotid Duct Sparing Radiation Therapy Planning
  • 2.Undergo Parotid Sparing Radiation Therapy Planning
  • 3.Use MRI sialography

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: The rate of xerostomia score based on the MD Anderson Symptom Inventory Head and Neck (MDASI - HN)- 12 months

Body systems

Oncology