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Study details
Enrolling now

MM402 for Autism Spectrum Disorder

Definium Therapeutics US, Inc.
NCT IDNCT07303907ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

20

Study length

about 1.7 years

Ages

18–65

Locations

1 site in NY

What this study is about

Researchers are testing a treatment called MM402, which is an R-enantiomer of MDMA (R-MDMA), in adults with autism spectrum disorder. The trial will last 636 days and involve approximately 20 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take MM402 (R-enantiomer of 3,4-methylenedioxymethamphetamine (MDMA))

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

oral

Endpoints

Primary: Change from Baseline in 11-point Numerical Rating Scale (NRS) scores

Secondary: Pharmacokinetic Parameters (AUC0-24h), Pharmacokinetic Parameters (AUC0-inf), Pharmacokinetic Parameters (Cmax), Pharmacokinetic Parameters (Tmax), Pharmacokinetic Parameters (t1/2), Pharmacokinetic Plasma concentrations

Body systems

Psychiatry / Mental Health