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Study details
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A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Merck Sharp & Dohme LLC
NCT IDNCT07318558ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Ages

18+

Sex

Female only

Locations

1 site in FL

What this study is about

This Phase 3 study is testing Bevacizumab in people with neoplasms. The primary outcome being measured is Progression-Free Survival (PFS).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

bevacizumab

Drug routes

infusion

Endpoints

Primary: Progression-Free Survival (PFS)

Secondary: Change From Baseline in Abdominal/Gastrointestinal (GI) Symptoms Combined Score Using the EORTC QLQ-Ovarian Cancer Module 28 (OV28), Change From Baseline in Global Health Status/Quality of Life (GHS/QoL) Combined Score (Items 29 and 30) Using the European Organisation for Research and Treatment of Cancer QoL Questionnaire-Core 30 (EORTC QLQ-C30), Change From Baseline in Physical Functioning Combined Score (Items 1 to 5) Using EORTC QLQ-C30, Change From Baseline in Role Functioning Combined Score (Items 6 and 7) Using EORTC QLQ-C30, Number of Participants Who Discontinue Study Treatment Due to an AE, Number of Participants Who Experience an Adverse Event (AE), Overall Survival (OS), Progression-Free Survival 2 (PFS2)

Body systems

Oncology