Study details
Enrolling now
Carbon Dioxide Administration and Brain Waste Clearance
Andrew Mayer
NCT IDNCT07357090ClinicalTrials.gov data as of Apr 2026
Target enrollment
200
Study length
about 6.1 years
Ages
18–82
Locations
1 site in NM
What this study is about
This trial is testing whether different levels of carbon dioxide can safely increase the movement of proteins from the brain into the blood, which could help clear waste products. The study will involve adults with or without a history of traumatic brain injury receiving varying doses of CO2 over several months.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Hypercapnia task performed during fMRI
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Primary: Protein Efflux (Surrogate Measure of Brain Waste Clearance)