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Study details
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A Study of Elenestinib in Healthy Adult Female Participants

Blueprint Medicines Corporation
NCT IDNCT07388511ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18–65

Sex

Female only

Locations

1 site in AZ

What this study is about

This Phase 1 study is testing Elenestinib in people with healthy volunteers. The primary outcome being measured is Apparent first-order terminal elimination half-life (t1/2).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralOral

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

kinase inhibitor, ethinylestradiol, progestin (hormonal contraceptive), midazolam (Benzodiazepine; short-acting)

Drug routes

oral (Oral Tablet), injection

Endpoints

Primary: Apparent first-order terminal elimination half-life (t1/2), Apparent total plasma clearance after oral administration (CL/F), Maximum observed concentration (Cmax), Percent of AUC0-inf extrapolated (AUC%extrap), Time to reach Cmax (Tmax)

Secondary: Number of participants with treatment-emergent adverse events (TEAEs)