Skip to content
Study details
Enrolling now

A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)

Merck Sharp & Dohme LLC
NCT IDNCT07388667ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18–60

Locations

5 sites in CA, FL, MO +1

What this study is about

This Phase 1 study is focused on people with healthy volunteers. The primary outcome being measured is Number of Participants Who Discontinue Study Treatment Due to an AE.

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Number of Participants Who Discontinue Study Treatment Due to an AE, Number of Participants Who Experience an Adverse Event (AE)

Secondary: Apparent Clearance (CL/F) of MK-4082, Apparent Terminal Half-life (t1/2) of MK-4082, Change from Baseline in Body Mass Index (BMI), Change from Baseline in Body Weight, Maximum Plasma Concentration (Cmax) of MK-4082, Time to Maximum Plasma Concentration (Tmax) of MK-4082