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Study details
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A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

M.D. Anderson Cancer Center
NCT IDNCT07401875ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18+

Locations

1 site in TX

What this study is about

This Phase 1 study is testing Nivolumab in people with hc 7366. The primary outcome being measured is Safety and adverse events (AEs).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

nivolumab (Immune checkpoint inhibitor; blocks PD-1 receptor on T cells), ipilimumab (Immune checkpoint inhibitor; blocks CTLA-4 on T cells)

Drug routes

infusion, injection (Injection)

Endpoints

Primary: Safety and adverse events (AEs)

Body systems

Oncology