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Study details
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A Study of GEN1106 in Participants With Solid Tumors

Genmab
NCT IDNCT07416123ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18+

Locations

3 sites in NY, SC, TX

What this study is about

This Phase 1 study is focused on people with solid tumors. The primary outcome being measured is Part 1 Dose Escalation: Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Part 1 Dose Escalation: Number of Participants with Adverse Events (AEs) and Serious Adverse Events (SAEs), Part 2 Dose Refinement: Number of Participants with AEs and SAEs, Part 3 Expansion: Objective Response Rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1

Secondary: Part 1 Dose Escalation and Part 2 Dose Refinement: Disease Control Rate (DCR) per RECIST v1.1, Part 1 Dose Escalation and Part 2 Dose Refinement: Duration of Response (DOR) per RECIST v1.1, Part 1 Dose Escalation and Part 2 Dose Refinement: ORR per RECIST v1.1, Part 3 Expansion: DCR per RECIST v1.1, Part 3 Expansion: DOR per RECIST v1.1, Part 3 Expansion: Number of Participants with AEs and SAEs

Body systems

Oncology