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Study details
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A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

EpiBiologics
NCT IDNCT07462377ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18+

Locations

5 sites in CA, NJ, TN +1

What this study is about

This Phase 1 study is focused on people with egfr. The primary outcome being measured is Evaluation of the safety and tolerability of EPI-326.

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Evaluation of the safety and tolerability of EPI-326

Secondary: Determination of area under the concentration-time curve (AUC), Determination of clearance (CL) from the blood, Determination of maximum (Cmax) and minimum (Cmin) plasma concentration, Duration of response (DOR), Objective response rate (ORR)

Body systems

Oncology, Respiratory