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Study details
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Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer

Generate Biomedicines
NCT IDNCT07484022ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Ages

18+

Locations

2 sites in FL, NY

What this study is about

This Phase 1 study is testing Pembrolizumab in people with advanced urothelial cancer. The primary outcome being measured is Incidence of AEs and SAEs.

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

pembrolizumab (Immune checkpoint inhibitor; blocks PD-1 to boost T-cell attack on cancer), enfortumab vedotin

Drug routes

infusion

Endpoints

Primary: Incidence of AEs and SAEs

Secondary: Pharmacokinetics of GB-4362

Body systems

Oncology