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Study details
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Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

Revolution Medicines, Inc.
NCT IDNCT07491445ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Ages

18+

Locations

2 sites in NV, OH

What this study is about

This Phase 3 study is testing gemcitabine in people with pancreatic adenocarcinoma. The primary outcome being measured is Overall survival (OS).

Simplified from trial records by PatientMatch.

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

gemcitabine, paclitaxel (Taxane chemotherapy; stabilizes microtubules)

Drug routes

injection (Injection), infusion

Endpoints

Primary: Overall survival (OS), Progression free survival (PFS)

Secondary: Duration of response (DOR), Health-related outcome assessed by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Pancreatic Cancer Module (EORTC QLQ-PAN26), Incidence of adverse events (AEs), Objective response rate (ORR), Quality of life as assessed with European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30)

Body systems

Oncology